Rapid molecular testing is associated with decreased broad-spectrum antibiotic use among patients with streptococcal bloodstream infections

Tyler Tate; J. Alex Viehman; Ryan K. Shields

doi:10.1017/ash.2024.430

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2024)

Rapid molecular testing is associated with decreased broad-spectrum antibiotic use among patients with streptococcal bloodstream infections

Tyler Tate,
J. Alex Viehman,
Ryan K. Shields

Affiliations

Tyler Tate: ORCiD; Department of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA
J. Alex Viehman: Department of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Ryan K. Shields: ORCiD; Department of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, USA Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, PA, USA Center for Innovative Antimicrobial Therapy, University of Pittsburgh, Pittsburgh, PA, USA

DOI: https://doi.org/10.1017/ash.2024.430
Journal volume & issue: Vol. 4

Abstract

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We investigated the impact of rapid diagnostic testing with real-time stewardship intervention on patients with Streptococcal bacteremia. Compared to pre-intervention, patients in the post-intervention group received more rapid antibiotic de-escalation (42 vs 88 h), and were more commonly de-escalated to narrow-spectrum (86% vs 52%) and oral antibiotics (30% vs 14%).

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

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