Comparison of Sigma metrics computed by three bias estimation approaches for 33 chemistry and 26 immunoassay analytes

Abstract

Sigma metric can be calculated using a simple equation. However, there are multiple sources for the elements in the equation that may produce different Sigma values. This study aimed to investigate the importance of different bias estimation approaches for Sigma metric calculation.

Keywords

• bias
• chemistry
• external quality assurance
• immunoassays
• internal quality control
• sigma metric