PLoS ONE (Jan 2022)

Assessment of hypokalemia and clinical prognosis in Patients with COVID-19 in Yangzhou, China.

  • Jiangtao Yin,
  • Nana Yuan,
  • Ziqiang Huang,
  • Zhenkui Hu,
  • Quanlei Bao,
  • Zhenli Shao,
  • Qiong Mei,
  • Yong Xu,
  • Wenli Wang,
  • Dadong Liu,
  • Li Zhao,
  • Shengxia Wan

DOI
https://doi.org/10.1371/journal.pone.0271132
Journal volume & issue
Vol. 17, no. 7
p. e0271132

Abstract

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BackgroundHypokalemia is a frequent electrolyte imbalance in patients with COVID-19. The aim of this study was to estimate the association between hypokalemia and clinical prognosis in patients with moderate COVID-19.MethodsA single-center, retrospective, observational study was conducted on 81 non-ICU admitted patients with moderate COVID-19 according to the criteria issued by the Chinese Health Bureau in the Third People's Hospital of Yangzhou (Northern Jiangsu People's Hospital New District Branch) from 4th to 25th August 2021. The demographic, clinical, and laboratory data were reviewed and collected, then the correlation between hypokalemia and prognosis was determined.ResultsThe level of serum potassium of patients ranged from 2.80 mmol/L to 4.70 mmol/L. Hypokalemia was detected in 39 out of the 81 included patients (48.15%) during hospitalization. Patients with hypokalemia had prolonged days of negative nucleic acid conversion and hospital stay. Correlation analysis showed that the level of serum potassium was negatively correlated with days of negative nucleic acid conversion and length of hospital stay. Bivariate logistic regression analysis proved that hypokalemia was a risk factor for prolonged hospital stay in patients with moderate COVID-19.ConclusionHypokalemia was prevalent in patients with moderate COVID-19 in Yangzhou, China. Hypokalemia was associated with the prolonged hospital stay in patients with moderate COVID-19.