Aggressive infantile fibromatosis: a case report

Abstract

Aggressive infantile fibromatosis encountered in infants and in childhood is an aggressive, infiltrating, non-metastasizing disease characterized by a benign neoplastic histology and has a tendency to recur locally when not excised adequately. Because of local aggressiveness and a high rate of recurrence, wide local excision must be performed by careful dissection preserving major vital structures. The role of radiotherapy in aggressive infantile fibromatosis has not been established, but cases of tumor regression have been observed with chemotherapy. A one-year-old boy was presented to our clinic with a congenital history of a mass in the left neck region. A fine-needle aspiration biopsy was performed when he was 3 months old in another institution and the result was fibromatosis histologically. In our clinic we performed ultrasonography and computerized tomography. The result of ultrasonography demonstrated that the mass was 6.5x7x5 centimeter and there were multiple lymphadenopathies greater than 1.5 centimeter in jugular chain and in posterior cervical region. In CT of the cervical region a heterogenic mass that originated from the sternocleidomastoid muscle was measured as 9x8x8 centimeter and it displaced the larynx to the right side. The mass was excised totally and there was no recurrence in two years follow-up period. Aggressive infantile fibromatosis must be always kept in mind in the differential diagnosis in infants and children that present with a cervical mass.

Keywords

• aggressive infantile fibromatosis
• recurrence
• metastasis.