Journal of Ophthalmic & Vision Research (Feb 2023)

A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma

  • Alexandra Van Brummen,
  • Sarah Jacobs,
  • Shu Feng,
  • Emily Li,
  • Arash J. Amadi

DOI
https://doi.org/10.18502/jovr.v18i1.12733
Journal volume & issue
Vol. 18, no. 1
pp. 1 – 2

Abstract

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Abstract Purpose: To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden. Case Report: A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO 2 laser-assisted topical steroid application, which resulted in lesion regression. Conclusion: A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.

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