Celiac disease: A rare cause of cirrhotic portal hypertension - A case report

Abstract

Celiac disease, triggered by gluten, rarely manifests as cirrhotic portal hypertension. We present the case of a 35-year-old male with concurrent cirrhosis and celiac disease, highlighting their complex relationship. The patient presented with diarrhea, fatigue, and anemia. Clinical examination revealed hepatosplenomegaly and cardiovascular abnormalities. Diagnostic assessments confirmed cirrhosis secondary to celiac disease. The patient received nutritional supplementation, intravenous therapies, and adhered to a gluten-free diet. Significant improvement was observed after three months. Celiac disease's extraintestinal manifestations include liver abnormalities, progressing to cirrhotic portal hypertension. Gluten removal is crucial for hepatic dysfunction resolution. This case emphasizes the rare occurrence of cirrhotic portal hypertension in celiac disease. A multidisciplinary approach and adherence to a gluten-free diet are pivotal for managing such cases. Understanding this intricate relationship is essential for comprehensive clinical assessments.

Keywords

• Celiac disease
• Cirrhotic portal hypertension
• Gastro-intestinal complications
• Extra-intestinal manifestations
• Case report