Juxtaglomerular cell tumor: a case report

Abstract

Abstract Introduction The tumor produces an excessive amount of renin resulting in secondary hyperaldosteronism, thereby causing hypertension with hypokalemia. The authors describe a case of reninoma in a young man, who presented with malignant hypertension. Case presentation A 35-year-old African male patient referred to our institution, presenting with severe hypertension for 4 years. Renal magnetic resonance imaging showed a solid 9-mm lesion in the right upper pole cortex with high signal intensity on diffusion-weighted imaging, isointense on T2, and enhanced after contrast injection. The patient underwent an open right partial nephrectomy. The diagnosis of reninomas was confirmed by histopathological examination. Conclusion Nephron-sparing surgery should be considered in patients with juxtaglomerular tumors. This technique allows prompt recovery with the preservation of significant renal function.

Keywords

• Atypical reninoma
• Case report
• Plasma renin activity
• Plasma renin concentration
• Reninoma