Crystal structure of 5-butylamino-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde obtained from a microwave-assisted reaction using caesium carbonate as catalyst

Abstract

The title compound, C14H18N4O, synthesized from an unconventional microwave-assisted method using caesium carbonate as catalyst, has an approximately planar conformation with the pyridyl and pyrazole rings inclined by a dihedral angle of 7.94 (3)°, allowing the formation of an intramolecular N—H...N hydrogen bond. The supramolecular assembly has a three-dimensional arrangement controlled mainly by weak C—H...O and C—H...π interactions.

Keywords

• crystal structure
• pharmaceutical compound
• 5-aminopyrazoles
• nucleophilic substitution
• hydrogen bonding