Changes in the serum concentrations of adhesion molecules and vascular endothelial growth factor in active ankylosing spondylitis patients taking amtolmetin guacil: Results of a 56-week prospective ореn-label controlled observational study

Abstract

Aim. To estimate changes in the concentrations of adhesion molecules and vascular endothelial growth factor A after 30-day additional use of amtolmetin guacil (AMG) in patients with active ankylosing spondylitis (AS) who were unresponsive to previous one-year treatment with nonsteroidal anti-inflammatory drugs (NSAIDs). Subjects and methods. 20 patients with active AS who had not reached a BASDAI score

Keywords

• ankylosing spondylitis
• nonsteroidal anti-inflammatory drugs
• amtolmetin guacil
• adhesion molecules
• vascular endothelial growth factors
• endothelial dysfunction