Revista da Sociedade Brasileira de Medicina Tropical ()

Clinical and laboratorial features of oral candidiasis in HIV-positive patients

  • Regiane Nogueira Spalanzani,
  • Karine Mattos,
  • Luiza Inahe Marques,
  • Pedro Fernando Diniz Barros,
  • Pamela Iruama Peres Pereira,
  • Anamaria Mello Miranda Paniago,
  • Rinaldo Poncio Mendes,
  • Marilene Rodrigues Chang

DOI
https://doi.org/10.1590/0037-8682-0241-2017
Journal volume & issue
Vol. 51, no. 3
pp. 352 – 356

Abstract

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Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.

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