Vaccines (Sep 2020)

<i>Pneumocystis jirevocii</i> and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients?

  • Maria A. De Francesco,
  • Federico Alberici,
  • Nicola Bossini,
  • Francesco Scolari,
  • Federico Pascucci,
  • Gabriele Tomasoni,
  • Arnaldo Caruso

DOI
https://doi.org/10.3390/vaccines8030544
Journal volume & issue
Vol. 8, no. 3
p. 544

Abstract

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COVID-19 might potentially give rise to a more severe infection in solid organ transplant recipients due to their chronic immunosuppression. These patients are at a higher risk of developing concurrent or secondary bacterial and fungal infections. Co-infections can increase systemic inflammation influencing the prognosis and the severity of the disease, and can in turn lead to an increased need of mechanical ventilation, antibiotic therapy and to a higher mortality. Here we describe, for the first time in Europe, a fatal case of co-infection between SARS-CoV-2 and Pneumocystis jirevocii in a kidney transplant recipient.

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