Nature Communications (Feb 2021)

Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19

  • Aakriti Gupta,
  • Mahesh V. Madhavan,
  • Timothy J. Poterucha,
  • Ersilia M. DeFilippis,
  • Jessica A. Hennessey,
  • Bjorn Redfors,
  • Christina Eckhardt,
  • Behnood Bikdeli,
  • Jonathan Platt,
  • Ani Nalbandian,
  • Pierre Elias,
  • Matthew J. Cummings,
  • Shayan N. Nouri,
  • Matthew Lawlor,
  • Lauren S. Ranard,
  • Jianhua Li,
  • Claudia Boyle,
  • Raymond Givens,
  • Daniel Brodie,
  • Harlan M. Krumholz,
  • Gregg W. Stone,
  • Sanjum S. Sethi,
  • Daniel Burkhoff,
  • Nir Uriel,
  • Allan Schwartz,
  • Martin B. Leon,
  • Ajay J. Kirtane,
  • Elaine Y. Wan,
  • Sahil A. Parikh

DOI
https://doi.org/10.1038/s41467-021-21553-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

Read online

Statins, which have anti-inflammatory and antithrombotic properties, could have effects in COVID-19 patients. Here, the authors find in a retrospective analysis of patients hospitalized with COVID-19 that antecedent statin use is associated with lower inpatient mortality.