Nanomaterials (Aug 2022)

Lipid-Based Nanomaterials for Drug Delivery Systems in Breast Cancer Therapy

  • Lekshmi Rethi,
  • Chinmaya Mutalik,
  • Dito Anurogo,
  • Long-Sheng Lu,
  • Hsiu-Yi Chu,
  • Sibidou Yougbaré,
  • Tsung-Rong Kuo,
  • Tsai-Mu Cheng,
  • Fu-Lun Chen

DOI
https://doi.org/10.3390/nano12172948
Journal volume & issue
Vol. 12, no. 17
p. 2948

Abstract

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Globally, breast cancer is one of the most prevalent diseases, inducing critical intimidation to human health. Lipid-based nanomaterials have been successfully demonstrated as drug carriers for breast cancer treatment. To date, the development of a better drug delivery system based on lipid nanomaterials is still urgent to make the treatment and diagnosis easily accessible to breast cancer patients. In a drug delivery system, lipid nanomaterials have revealed distinctive features, including high biocompatibility and efficient drug delivery. Specifically, a targeted drug delivery system based on lipid nanomaterials has inherited the advantage of optimum dosage and low side effects. In this review, insights on currently used potential lipid-based nanomaterials are collected and introduced. The review sheds light on conjugation, targeting, diagnosis, treatment, and clinical significance of lipid-based nanomaterials to treat breast cancer. Furthermore, a brighter side of lipid-based nanomaterials as future potential drug delivery systems for breast cancer therapy is discussed.

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