Туберкулез и болезни лёгких (Apr 2018)
ROLE OF GENITAL TUBERCULOSIS IN UNFAVORABLE OUTCOMES OF IN VITRO FERTILIZATION
Abstract
Prospective integral laboratory and instrumental examinations were performed in 110 infertile women The examined women were divided into 2 groups: the main group included 60 patients with infertility associated with genital tuberculosis, while the control group included 50 women with infertility of non-tuberculous etiology (control group) 16 couples from the main group and 17 couples from the control group had their fertility restored through in vitro fertilization Take-home baby rate, which is the main rate reflecting IVF efficiency was lower in case of tuberculosis-associated infertility compared to the control group (2353% versus 375%), while the frequency of spontaneous abortions was higher (250% and 176%) The lack of timely diagnostics and treatment of latent tuberculous infection (25%) and endometrial lesions (50%) are the main causes of unfavorable outcomes of IVF Pregnancy resulting from IVF in case of infertility due to tuberculosis is associated with high risks of complicated gestation, premature birth, maternal and perinatal diseases.
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