Kafkas Universitesi Veteriner Fakültesi Dergisi (Mar 2018)

In vitro evaluation of bioactivity of dictyonella incisa from turkey

  • Hajar HEYDARI,
  • Bülent GÖZCELİOĞLU,
  • Belma KONUKLUGİL

DOI
https://doi.org/10.9775/kvfd.2018.19309
Journal volume & issue
Vol. 24, no. 3
pp. 479 – 482

Abstract

Read online

Marine sources are known to produce structurally unique pharmaceutically potent secondary metabolites. During the course of our studies on Turkish marine sponges, we have collected Dictyonella incisa from Turkey"s coast and methanolic extract was investigated for antioxidant, cytotoxic and antimicrobial activity. Antioxidant activity was evaluated by the superoxide radical scavenging assay, cytotoxic activity was determined against HCT-116 and HEp-2 cell lines by MTT assay. Antimicrobial activity was tested against some Gram positive, Gram negative bacteria and yeasts. Also cholesterol and cholestane isolated and the structure were identified by NMR methods. This is the first work on the bioactivity and secondary metabolites of D. incisa collected from Turkish coasts.

Keywords