npj Schizophrenia (Feb 2021)

Accuracy of self-assessment of real-life functioning in schizophrenia

  • Paola Rocca,
  • Claudio Brasso,
  • Cristiana Montemagni,
  • Silvio Bellino,
  • Alessandro Rossi,
  • Alessandro Bertolino,
  • Dino Gibertoni,
  • Eugenio Aguglia,
  • Mario Amore,
  • Ileana Andriola,
  • Antonello Bellomo,
  • Paola Bucci,
  • Antonino Buzzanca,
  • Bernardo Carpiniello,
  • Alessandro Cuomo,
  • Liliana Dell’Osso,
  • Angela Favaro,
  • Giulia Maria Giordano,
  • Carlo Marchesi,
  • Palmiero Monteleone,
  • Lucio Oldani,
  • Maurizio Pompili,
  • Rita Roncone,
  • Rodolfo Rossi,
  • Alberto Siracusano,
  • Antonio Vita,
  • Patrizia Zeppegno,
  • Silvana Galderisi,
  • Mario Maj,
  • the Italian Network for Research on Psychoses

DOI
https://doi.org/10.1038/s41537-021-00140-9
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 10

Abstract

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Abstract A consensus has not yet been reached regarding the accuracy of people with schizophrenia in self-reporting their real-life functioning. In a large (n = 618) cohort of stable, community-dwelling schizophrenia patients we sought to: (1) examine the concordance of patients’ reports of their real-life functioning with the reports of their key caregiver; (2) identify which patient characteristics are associated to the differences between patients and informants. Patient-caregiver concordance of the ratings in three Specific Level of Functioning Scale (SLOF) domains (interpersonal relationships, everyday life skills, work skills) was evaluated with matched-pair t tests, the Lin’s concordance correlation, Somers’ D, and Bland–Altman plots with limits of agreement (LOA). Predictors of the patient-caregiver differences in SLOF ratings were assessed with a linear regression with multivariable fractional polynomials. Patients’ self-evaluation of functioning was higher than caregivers’ in all the evaluated domains of the SLOF and 17.6% of the patients exceeded the LOA, thus providing a self-evaluation discordant from their key caregivers. The strongest predictors of patient-caregiver discrepancies were caregivers’ ratings in each SLOF domain. In clinically stable outpatients with a moderate degree of functional impairment, self-evaluation with the SLOF scale can become a useful, informative and reliable clinical tool to design a tailored rehabilitation program.