Clinical and Translational Allergy (Jan 2020)
Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper
- Valerie Hox,
- Evelijn Lourijsen,
- Arnout Jordens,
- Kristian Aasbjerg,
- Ioana Agache,
- Isam Alobid,
- Claus Bachert,
- Koen Boussery,
- Paloma Campo,
- Wytske Fokkens,
- Peter Hellings,
- Claire Hopkins,
- Ludger Klimek,
- Mika Mäkelä,
- Ralph Mösges,
- Joaquim Mullol,
- Laura Pujols,
- Carmen Rondon,
- Michael Rudenko,
- Sanna Toppila-Salmi,
- Glenis Scadding,
- Sophie Scheire,
- Peter-Valentin Tomazic,
- Thibaut Van Zele,
- Martin Wagemann,
- Job F. M. van Boven,
- Philippe Gevaert
Affiliations
- Valerie Hox
- Cliniques Universitaires Saint-Luc Brussels
- Evelijn Lourijsen
- Department of Otorhinolaryngology, Amsterdam University Medical Centres, AMC
- Arnout Jordens
- Upper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University Hospital
- Kristian Aasbjerg
- Bispebjerg University Hospital
- Ioana Agache
- Faculty of Medicine, Transsylvania University
- Isam Alobid
- Hospital Clínic, IDIBAPS, CEBERES Universitat de Barcelona
- Claus Bachert
- Upper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University Hospital
- Koen Boussery
- Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University
- Paloma Campo
- Allergy Unit, Hospital Regional Universitario of Málaga, IBIMA, ARADyAL
- Wytske Fokkens
- Department of Otorhinolaryngology, Amsterdam University Medical Centres, AMC
- Peter Hellings
- Department of Ear, Nose and Throat Disease, University Hospitals
- Claire Hopkins
- ENT Department, Guy’s & St Thomas’ Hospital
- Ludger Klimek
- Center of Rhinology and Allergology
- Mika Mäkelä
- Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki
- Ralph Mösges
- University of Cologne
- Joaquim Mullol
- Hospital Clínic, IDIBAPS, CEBERES Universitat de Barcelona
- Laura Pujols
- Hospital Clínic, IDIBAPS, CEBERES Universitat de Barcelona
- Carmen Rondon
- Allergy Unit, Hospital Regional Universitario of Málaga, IBIMA, ARADyAL
- Michael Rudenko
- London Allergy and Immunology Center
- Sanna Toppila-Salmi
- Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki
- Glenis Scadding
- Royal National Throat, Nose and Ear Hospital
- Sophie Scheire
- Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University
- Peter-Valentin Tomazic
- Medical University Graz
- Thibaut Van Zele
- Upper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University Hospital
- Martin Wagemann
- Heinrich-Heine-University
- Job F. M. van Boven
- Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen
- Philippe Gevaert
- Upper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University Hospital
- DOI
- https://doi.org/10.1186/s13601-019-0303-6
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 27
Abstract
Abstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.
Keywords
