Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, Canada
Tommy Alain
Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, Canada
Ivan Topisirovic
Department of Oncology and Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Canada
Nahum Sonenberg
Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, Canada
Polysome profiling is a method that allows monitoring of translation activity of mRNAs in cells and tissues. Once each polysome fractions are collected, the translation activity of each mRNA is analyzed using various molecular biology techniques such as Northern blotting, RT-PCR, microarray or deep-sequencing.
