Changes in the expression of TLR2 during the intestinal phase of trichinellosis

Abstract

Toll-like receptors (TLRs) play an important role in fast activation of the immune response to a variety of pathogens, including parasites. In this study, we focused on TLR2, because this receptor is one of the best known and most frequently analysed members of the TLR family. The aim of this study was to assess the effect of Trichinella spiralis on expression of TLR2 during the intestinal stage of infection.

Keywords

• mice
• trichinella spiralis
• toll-like receptor 2
• quantitative real-time pcr
• immunohistochemical staining