Mitapivat, a pyruvate kinase activator, improves transfusion burden and reduces iron overload in β-thalassemic mice

• Alessandro Mattè,
• Penelope A. Kosinski,
• Enrica Federti,
• Lenny Dang,
• Antonio Recchiuti,
• Roberta Russo,
• Angela Siciliano,
• Veronica Riccardi,
• Anne Janin,
• Matteo Mucci,
• Christophe Leboeuf,
• Achille Iolascon,
• Carlo Brugnara,
• Lucia De Franceschi

Affiliations

Alessandro Mattè

University of Verona and AOUI Verona, Verona

Penelope A. Kosinski

Agios Pharmaceuticals, Inc., Cambridge, MA

Enrica Federti

University of Verona and AOUI Verona, Verona

Lenny Dang

Agios Pharmaceuticals, Inc., Cambridge, MA

Antonio Recchiuti

Dept. of Medical, Oral and Biotechnology Science, “G. d’Annunzio” University of Chieti, Chieti

Roberta Russo

Dept. of Molecular Medicine and Medical Biotechnology and CEINGE, University of Naples Federico II, Naples

Angela Siciliano

University of Verona and AOUI Verona, Verona

Veronica Riccardi

University of Verona and AOUI Verona, Verona

Anne Janin

University Diderot of Paris, Paris

Matteo Mucci

Dept. of Medical, Oral and Biotechnology Science, “G. d’Annunzio” University of Chieti, Chieti

Christophe Leboeuf

University Diderot of Paris, Paris

Achille Iolascon

Dept. of Molecular Medicine and Medical Biotechnology and CEINGE, University of Naples Federico II, Naples

Carlo Brugnara

Department of Laboratory Medicine, Harvard Medical School, Boston Children's Hospital, Boston, MA (USA)

Lucia De Franceschi

University of Verona and AOUI Verona, Verona