Nature Communications (Jun 2021)

SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells

  • Jae Hyung Jung,
  • Min-Seok Rha,
  • Moa Sa,
  • Hee Kyoung Choi,
  • Ji Hoon Jeon,
  • Hyeri Seok,
  • Dae Won Park,
  • Su-Hyung Park,
  • Hye Won Jeong,
  • Won Suk Choi,
  • Eui-Cheol Shin

DOI
https://doi.org/10.1038/s41467-021-24377-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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T cells are instrumental to protective immune responses against SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic. Here the authors show that, in convalescent COVID-19 patients, memory T cell responses are detectable up to 317 days post-symptom onset, in which the presence of stem cell-like memory T cells further hints long-lasting immunity.