Scientific Reports (Nov 2023)

Association of C-reactive protein with mortality in Covid-19 patients: a secondary analysis of a cohort study

  • Fei Li,
  • Mingjun He,
  • Mingchao Zhou,
  • Yuyao Lai,
  • Yongjie Zhu,
  • Ziji Liu,
  • Yulong Wang,
  • Yao Wang

DOI
https://doi.org/10.1038/s41598-023-47680-x
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

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Abstract Our study aimed to explore the association between serum C-reactive protein (CRP) and COVID‐19 mortality. This is a retrospective cohort study of all patients admitted to 4 hospitals within the Montefiore Health System between March 1 and April 16, 2020, with SARS-CoV-2 infection. All-cause mortality were collected in 7 May 2020. The mortality risk was estimated using Cox proportional hazards models. Of the 3545 patients with a median age of 63.7 years, 918 (25.9%) died within the time of cohort data collection after admission. When the CRP was 15.6 mg/L, with the increase of CRP, the mortality rate increases relatively flat.