Nature Communications (Jun 2018)

UBXN3B positively regulates STING-mediated antiviral immune responses

  • Long Yang,
  • Leilei Wang,
  • Harshada Ketkar,
  • Jinzhu Ma,
  • Guang Yang,
  • Shuang Cui,
  • Tingting Geng,
  • Dana G. Mordue,
  • Toyoshi Fujimoto,
  • Gong Cheng,
  • Fuping You,
  • Rongtuan Lin,
  • Erol Fikrig,
  • Penghua Wang

DOI
https://doi.org/10.1038/s41467-018-04759-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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The UBXN proteins are likely involved in a diverse range of biological processes, but their physiological functions remain largely unknown. Here the authors show that UBXN3B positively regulates STING-mediated immune responses in the context of viral infections.