Singling out how genes are regulated during development

Abstract

In this issue of Cell Genomics, McGarvey et al. characterize chromatin accessibility and gene regulation at single-cell resolution in the zebrafish embryo 24 h after fertilization, providing a valuable resource. Their findings add another important piece to understanding the dynamic landscape of gene expression and regulation during early vertebrate development and hint at the dramatic changes single-cell genomics is bringing to the field of developmental biology.