Hypomelanotic melanoma detected by the “little red riding hood sign” in a patient with neurofibromatosis type 1

Abstract

Neurofibromatosis type 1 (NF1) is a genetic disorder commonly associated with an increased risk for development of malignancy, including skin cancers. Herein we describe a case of invasive melanoma occurring in a patient with NF1 and discuss the association between these two diseases, highlighting the importance of comparative clinical and dermoscopic approach in this category of patients in which the detection of melanoma can be difficult by the presence of multiple skin tumors.

Keywords

• neurofibromatosis type 1
• melanoma
• dermoscopy