Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ (Feb 2015)

LUMINESCENCE DETERMINATION OF ETODOLAC

  • A. V. Yegorova,
  • Yu. V. Skrypynets,
  • I. I. Leonenko,
  • G. V. Anelchуk,
  • E. V. Malinka

DOI
https://doi.org/10.18524/2304-0947.2014.1(49).38316
Journal volume & issue
Vol. 19, no. 1(49)
pp. 45 – 51

Abstract

Read online

A highly sensitive, simple and rapid method for determination of non-steroidal anti- inflammatory drug – etodolac (Et) in washings from surfaces of pharmaceutical equipment have been proposed. The intensity of native luminescence of water-n-propanol solutions of etodolac (λex= 274 nm; λlum= 350 nm) was used as the analytical signal. The calibration graph is linear in the concentration range 0.014-2.3 μg/ml, the limit of detection is 0.5 ng/ml.

Keywords