Serum inhibin B values in infertile patients

Abstract

The increased interest in inhibin B generated by Sertoli cells is due to the fact that on the basis of findings, some authors recorded a relationship between the level of this hormone and infertility. The paper gives the results of an investigation of male sex hormones (inhibin B, follicle-stimulating and anti-Müllerian hormones) in the serum of patients with azoospermia (Group 1), who had spermatogenesis, as evidenced by testicular biopsy, who had no spermatogenesis (Group 2), and who had oligoasthenozoospermia (Group 3). The investigation indicated that Group 1 had a normal inhibin B level that was more than twice lower in Group 2. In addition, the latter group was recorded to have elevated follicle-stimulating hormone levels and low anti-Müllerian hormone concentrations as compared to Group 1.

Keywords

• infertility
• azoospermia
• inhibin b
• follicle-stimulating hormone
• testicular biopsy
• spermatogenesis