Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

• Renate De Smedt,
• Sofie Peirs,
• Julie Morscio,
• Filip Matthijssens,
• Juliette Roels,
• Lindy Reunes,
• Beatrice Lintermans,
• Steven Goossens,
• Tim Lammens,
• Nadine Van Roy,
• Aurore Touzart,
• Silvia Jenni,
• Yi-Chien Tsai,
• Federica Lovisa,
• Lara Mussolin,
• Valentina Serafin,
• Filip Van Nieuwerburgh,
• Dieter Deforce,
• Anne Uyttebroeck,
• Thomas Tousseyn,
• Birgit Burkhardt,
• Wolfram Klapper,
• Barbara De Moerloose,
• Yves Benoit,
• Elizabeth Macintyre,
• Jean-Pierre Bourquin,
• Giuseppe Basso,
• Benedetta Accordi,
• Beat Bornhauser,
• Jules Meijerink,
• Peter Vandenberghe,
• Pieter Van Vlierberghe

Affiliations

Renate De Smedt

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Sofie Peirs

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Julie Morscio

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Filip Matthijssens

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Juliette Roels

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium;Diagnostic Sciences, Ghent University, Belgium

Lindy Reunes

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Beatrice Lintermans

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Steven Goossens

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium;Molecular and Cellular Oncology Lab, Department for Biomedical Molecular Biology, Ghent University, Belgium

Tim Lammens

Cancer Research Institute Ghent (CRIG), Belgium;Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Belgium

Nadine Van Roy

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium

Aurore Touzart

Department of Hematology, APHP-Hôpital Necker, Paris, France

Silvia Jenni

Department of Oncology, and Children’s Research Center, University Children’s Hospital Zurich, Switzerland

Yi-Chien Tsai

Department of Oncology, and Children’s Research Center, University Children’s Hospital Zurich, Switzerland

Federica Lovisa

Department of Woman’s and Child’s Health, Hematology-Oncology Laboratory, Istituto di Ricerca Pediatrica (IRP) and University of Padova, Italy

Lara Mussolin

Department of Woman’s and Child’s Health, Hematology-Oncology Laboratory, Istituto di Ricerca Pediatrica (IRP) and University of Padova, Italy

Valentina Serafin

Department of Woman’s and Child’s Health, Hematology-Oncology Laboratory, Istituto di Ricerca Pediatrica (IRP) and University of Padova, Italy

Filip Van Nieuwerburgh

Laboratory of Pharmaceutical Biotechnology, Ghent University, Belgium

Dieter Deforce

Laboratory of Pharmaceutical Biotechnology, Ghent University, Belgium

Anne Uyttebroeck

Department of Pediatric Hematology-Oncology, University Hospitals Leuven, Belgium;Department of Oncology, KU Leuven, Belgium

Thomas Tousseyn

Translational Cell and Tissue Research laboratory, KU Leuven, Belgium

Birgit Burkhardt

Department of Pediatric Hematology and Oncology, University of Münster, Germany

Wolfram Klapper

Department of Pathology, Hematopathology Section, UKSH Campus Kiel, Germany

Barbara De Moerloose

Cancer Research Institute Ghent (CRIG), Belgium;Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Belgium

Yves Benoit

Cancer Research Institute Ghent (CRIG), Belgium;Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Belgium

Elizabeth Macintyre

Department of Hematology, APHP-Hôpital Necker, Paris, France

Jean-Pierre Bourquin

Department of Oncology, and Children’s Research Center, University Children’s Hospital Zurich, Switzerland

Giuseppe Basso

Department of Woman’s and Child’s Health, Hematology-Oncology Laboratory, Istituto di Ricerca Pediatrica (IRP) and University of Padova, Italy

Benedetta Accordi

Department of Woman’s and Child’s Health, Hematology-Oncology Laboratory, Istituto di Ricerca Pediatrica (IRP) and University of Padova, Italy

Beat Bornhauser

Department of Oncology, and Children’s Research Center, University Children’s Hospital Zurich, Switzerland

Jules Meijerink

The Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands

Peter Vandenberghe

Department of Hematology, University Hospitals Leuven, Belgium;Center for Human Genetics, KU Leuven, Belgium

Pieter Van Vlierberghe

Department of Biomolecular Medicine, Ghent University, Belgium;Cancer Research Institute Ghent (CRIG), Belgium