Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites

Abstract

Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver tumor that affects young adults, with unknown biology. We present a case of 21‐yr‐old female with a liver tumor revealed by hemangioma feature at first presentation, after few months, presented with metastatic liver cancer. In pathologic investigation fibrolamellar hepatocellular carcinoma was confirmed. In spite of liver mass resection and lung metastasectomy, after short time, tumor recurrence was occurred. In 18F-FDG PET-CT scan ,lung, ovary, colon and peritoneal invasion was reported. Unfortunately, The patient died one year after diagnosis with rapid progression and multiple unusual metastatic site. Here, we also review the literature concerning FLHCC in many aspects.

Keywords

• Fibrolamellar Hepatocellular Carcinoma
• HCC
• Metastasis