Adverse cutaneous reactions to drugs (CDRs) at the General Teaching Hospital “Dr. Agostinho Neto”, Guantánamo 2018-2019

Abstract

Introduction: no studies in reference to adverse cutaneous reactions to drugs (CDRs) have been found at Guantanamo, need felt by the local dermatology faculty. Objective: characterize the adverse cutaneous reactions to drugs in patients treated at the Dermatology Service of the General Teaching Hospital "Dr. Agostinho Neto" in Guantanamo, period 2018-2019. Method: a descriptive and transversal study was carried out with all patients (N=75) with the diagnosis of adverse cutaneous reactions to drugs referred to the Dermatology Clinic of the General Teaching Hospital "Dr. Agostinho Neto, the drug that caused the reaction, clinical diagnosis, type of reaction, time from ingestion of the drug until the symptoms appeared, number of reactions and medical behaviour were specified. Results: These reactions were more common in patients using ibuprofen (18.7%), the most frequent clinical form was erythema multiforme minor (82.7%), above all were mild reactions (94.8%), which occurred more often at 10 ± 2.1 days of using the drug. 97.4% of patients were treated on an outpatient basis. Conclusions: the (CDRs) does not constitute a health problem in the Dermatology Service of the General Teaching Hospital "Dr. Agostinho Neto", they present a clinical spectrum consistent with what is endorsed in the scientific literature, but it is noted that the diagnosis is not usually as early as demand, because patients usually request medical evaluation after a period exceeding seven days.

Keywords

• reacciones cutáneas
• reacciones adversas medicamentosas
• toxicodermias