Journal of Chemistry (Jan 2021)

Investigation of the Chemical Composition and Antioxidant and Antimicrobial Activities of Lobularia maritima: Potent Therapeutic Applications

  • Soumaya Kouidhi,
  • Oumaima Zidi,
  • Soukaina Abdelwahed,
  • Yasmine Souissi,
  • Najla Trabelsi,
  • Alaeddine Redissi,
  • Manel Hamdi,
  • Emna Trabelsi,
  • Yosra Amara,
  • Taher Bhiri,
  • Rim Khrouf,
  • Boulbaba Selmi,
  • Sami Achour,
  • Ameur Cherif,
  • Wissem Mnif,
  • Amor Mosbah

DOI
https://doi.org/10.1155/2021/1981680
Journal volume & issue
Vol. 2021

Abstract

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Lobularia maritima, commonly known as sweet alyssum, is an annual ornamental halophyte widely spread along the Tunisian seashore. However, little is known about the phytochemical, antioxidant, and antimicrobial activities of Lobularia maritima. The present study aimed to investigate the potential biological properties of different parts (flowers, leaves, roots, and stems) of Tunisian L. maritima using diverse extraction methods. Extracts were then studied for their antioxidant properties, and the highest antioxidant activity was presented in the roots’ fractions. Added to this, flower, leaf, and root fractions showed interesting antimicrobial and antifungal activities against different Gram+ and Gram− bacteria and against Aspergillus ochraceus. Finally, the most active fractions (presenting the highest biological activities) were analyzed using silica gel purification and mass spectrometry coupled to gas chromatography (GC-MS) analysis, and different compounds were identified such as camphor, amide of oleic acids, tributyl acetylcitrate, betulinaldehyde, menthol, 1′-(butyn-3-one-1-yl)-, (1S, 2S, 5R), benzyl benzoate, 7-acetyl-6-ethyl-1,1,4,4-tetramethyltetralin, 2,4-heptadienal, (E,E), and nootkaton-11,12-epoxide. This work represents the first in-depth investigation of the content of bioactive compounds from Lobularia maritima. This species could potentially be a promising source of useful compounds for therapeutic applications.