Química Nova (Jan 2012)

Estudo fitoquímico e avaliação da atividade anti-inflamatória de Aeschynomene fluminensis vell. (Fabaceae)

  • Marlene Capelin Ignoato,
  • Rodrigo Monteiro Fabrão,
  • Ivânia Teresinha Albrecht Schuquel,
  • Marcos Felipe Pinatto Botelho,
  • Silvana Maria de Oliveira Santin,
  • Laura Lícia Milani de Arruda,
  • Ciomar Aparecida Bersani-Amado,
  • Maria Conceição de Souza

DOI
https://doi.org/10.1590/S0100-40422012001100028
Journal volume & issue
Vol. 35, no. 11
pp. 2241 – 2244

Abstract

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Phytochemical investigation of Aeschynomene fluminensis leaves and branches led to isolation of the flavonoid glycosides kaempferol 3,7-di-O-α-L-rhamnopyranoside, kaempferol 7-O-α-L-rhamnopyranoside, kaempferol 3-O-apiofuranosil-7-O- rhamnopyranoside, quercitin 3-O-α-L-rhamnopyranoside, quercitin 3-O-arabinofuranoside, 8-β-D-glucopyranosyl 4',5,7-trihydroxyflavanone, the isoflavonoid 4',7-di-hydroxy-isoflavone, the dimer epicatechin-(2β→7, 4β→8)- epicatechin, the polyol 3-O-methyl-chiro-inositol and two steroids in sitosterol and stigmasterol mixture. These compounds were identified by NMR ¹H and 13C and compared with literature data. Anti-inflammatory activity of the crude methanolic extract and its fractions was evaluated.

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