Nature Communications (Jul 2021)

Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing

  • Soumya Banerjee,
  • Samuel Vernon,
  • Wei Jiao,
  • Ben Jiwon Choi,
  • Evelyne Ruchti,
  • Jamshid Asadzadeh,
  • Olivier Burri,
  • R. Steven Stowers,
  • Brian D. McCabe

DOI
https://doi.org/10.1038/s41467-021-24490-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Synaptic structures disintegrate and fragment as ageing progresses. Here the authors find that miniature neurotransmission is required to maintain adult motor synapse structures in Drosophila and that increasing miniature events can preserve motor ability during ageing.