Features of chronic hepatitis C in a patient with metabolic syndrome (clinical case)

Abstract

Objective:To study the features of chronic hepatitis C in a 17-year-old patient with metabolic syndrome. Results: The article presents a clinical example of the course of chronic hepatitis C (HCV) in a 17-year-old patient with metabolic syndrome. He fell ill at the age of 13 and was seen by an infectious disease specialist. Antiviral therapy was not prescribed. A complete examination was conducted with an assessment of laboratory data. Biochemical activity, severity of liver fibrotic changes and signs of metabolic syndrome (MS) were compared. To assess the component composition of the body, a bioimpedance analysis was performed. Additionally, in order to identify associative links between gene polymorphism and MS components, the genetic profile of the patient and his parents was studied. Conclusion: A patient with genetic predictors of metabolic syndrome should be previously prescribed antiviral therapy for chronic hepatitis C.

Keywords

• chronic hepatitis c
• metabolic syndrome
• genetic predictors
• abdominal obesity
• dyslipidemia
• insulin resistance