An Integrated Strategy for Nutraceuticals from <i>Haematoccus pluvialis</i>: From Cultivation to Extraction

Sanjeet Mehariya; Neeta Sharma; Angela Iovine; Patrizia Casella; Tiziana Marino; Vincenzo Larocca; Antonio Molino; Dino Musmarra

doi:10.3390/antiox9090825

Antioxidants (Sep 2020)

An Integrated Strategy for Nutraceuticals from <i>Haematoccus pluvialis</i>: From Cultivation to Extraction

Sanjeet Mehariya,
Neeta Sharma,
Angela Iovine,
Patrizia Casella,
Tiziana Marino,
Vincenzo Larocca,
Antonio Molino,
Dino Musmarra

Affiliations

Sanjeet Mehariya: Department of Engineering, University of Campania “Luigi Vanvitelli”, Real Casa dell’Annunziata, Via Roma 29, 81031 Aversa (CE), Italy
Neeta Sharma: ENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Department of Sustainability-CR Trisaia, SS Jonica 106, km 419 + 500, 75026 Rotondella (MT), Italy
Angela Iovine: Department of Engineering, University of Campania “Luigi Vanvitelli”, Real Casa dell’Annunziata, Via Roma 29, 81031 Aversa (CE), Italy
Patrizia Casella: ENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Department of Sustainability-CR Portici, P. Enrico Fermi, 1, 80055 Portici (NA), Italy
Tiziana Marino: Department of Engineering, University of Campania “Luigi Vanvitelli”, Real Casa dell’Annunziata, Via Roma 29, 81031 Aversa (CE), Italy
Vincenzo Larocca: ENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Department of Sustainability-CR Trisaia, SS Jonica 106, km 419 + 500, 75026 Rotondella (MT), Italy
Antonio Molino: ENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Department of Sustainability-CR Portici, P. Enrico Fermi, 1, 80055 Portici (NA), Italy
Dino Musmarra: Department of Engineering, University of Campania “Luigi Vanvitelli”, Real Casa dell’Annunziata, Via Roma 29, 81031 Aversa (CE), Italy

DOI: https://doi.org/10.3390/antiox9090825
Journal volume & issue: Vol. 9, no. 9
p. 825

Abstract

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The aim of this study was to develop an effective integrated cultivation system for Haematococcus pluvialis as a source of bioactive compounds such as astaxanthin, lutein, proteins, and fatty acids (FAs). The Chlorophyta H. pluvialis was cultivated in a vertical bubble column photobioreactor (VBC-PBR) under batch mode, allowing switching from green to red phase for astaxanthin induction. The combined effect of light intensity and nutrients on bioactive compound formation was investigated. Results showed that growth under lower nutrients availability and light intensity led to a higher concentration of biomass. Growth under high light intensity with an appropriate concentration of nitrate, sulfate, phosphate and magnesium led to ~85% and ~58% higher production of total carotenoids and fatty acids, respectively. Under high stress conditions, ~90% nitrate and phosphate consumption were observed.

Published in Antioxidants

ISSN: 2076-3921 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://www.mdpi.com/journal/antioxidants

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