Life (Jun 2024)

Predicting Factors and Clinical Characteristics of Pruritus in Psoriasis: A Cross-Sectional Survey

  • Silviu-Horia Morariu,
  • Ovidiu Simion Cotoi,
  • Oana Mirela Tiucă,
  • Mircea Ambros,
  • Roxana-Ioana Ilcuș,
  • Liuba Garaga,
  • Ailincăi Raluca,
  • Diana Horea,
  • Andreea-Beatrix Bălan,
  • Mădălina Husariu,
  • Anca Gînj,
  • Alexandra Țiplic,
  • Andrea Hidi,
  • Biborka Szabo,
  • Radu Alexandru Stan,
  • Alin Codruț Nicolescu

DOI
https://doi.org/10.3390/life14070827
Journal volume & issue
Vol. 14, no. 7
p. 827

Abstract

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Pruritus is an important symptom among patients affected by psoriasis. To date, no general agreement has been established regarding pruritus as a measure of psoriasis severity. This study aims to assess psoriatic pruritis prevalence and characteristics using a comprehensive itch questionnaire. A semi-structured questionnaire consisting of 48 questions was applied to patients diagnosed with psoriasis and admitted to the Dermatology Department of Mures Clinical County Hospital, Romania. A total of 163 patients were enrolled, out of which 115 (70.55%) reported itch. Patients with itch had higher PASI (p = 0.003) and DLQI scores (p p p < 0.0001). Advanced age, high BMI, and PASI scores were indicators of itch presence, while female gender, high PASI score, and frequent itch episodes indicate highly intense pruritus (≥7 on the VAS). A better understanding of itch and its clinical features will guide physicians toward the best treatment option and would, ultimately, benefit the patient.

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