Comparison of impulse oscillometry measurements according to body mass index in patients with asthma

Abstract

Abstract Background Obesity can lead to increased airway resistance, especially in the peripheral airways. Impulse oscillometry (IOS) may detect small airway changes in asthma. In this study, we aimed to investigate the effect of obesity on the small airways of the lungs in asthmatic patients by IOS measurements. Methods One hundred newly diagnosed asthmatic patients (28 male) were divided into three groups (BMI ( 0.05). There were significant differences regarding R5, R5%, R20%, X5, X20, Fres, and R5-R20 among the three groups. Group 1 significantly differed about R5-R20, X5, AX, and Fres compared to groups 2 and 3 in pairwise comparisons. Based on these results, a difference was detected between BMI 0.05). Conclusion Obesity and being overweight affected peripheral airways and reactance; however, obesity also affects central airways, based on our results. In addition, it was thought that IOS may detect earlier than PFTs on small airway changes.

Keywords

• Asthma
• Small airways
• Impulse oscillometry
• Obesity