Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease

William T. Hu; Tugba Ozturk; Alexander Kollhoff; Whitney Wharton; J. Christina Howell; Alzheimer’s Disease Neuroimaging Initiative

doi:10.1038/s41467-021-24220-7

Nature Communications (Jun 2021)

Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease

William T. Hu,
Tugba Ozturk,
Alexander Kollhoff,
Whitney Wharton,
J. Christina Howell,
Alzheimer’s Disease Neuroimaging Initiative

Affiliations

William T. Hu: Department of Neurology and Center for Neurodegenerative Diseases, School of Medicine, Emory University
Tugba Ozturk: Department of Neurology and Center for Neurodegenerative Diseases, School of Medicine, Emory University
Alexander Kollhoff: Department of Neurology and Center for Neurodegenerative Diseases, School of Medicine, Emory University
Whitney Wharton: Nell Hodgson School of Nursing, Emory University
J. Christina Howell: Department of Neurology and Center for Neurodegenerative Diseases, School of Medicine, Emory University
Alzheimer’s Disease Neuroimaging Initiative

DOI: https://doi.org/10.1038/s41467-021-24220-7
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 12

Abstract

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Neuroinflammation is observed in Alzheimer’s disease. Here the authors show that 15 proteins related to inflammation found in CSF can potentially be used as a prognostic biomarker.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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