Indian Journal of Paediatric Dermatology (Jan 2022)

Successful treatment of juvenile generalized pustular psoriasis with secukinumab monotherapy. A case report and review of the literature

  • Raghavendra Rao,
  • Krithiga Muralidharan,
  • Varsha M Shetty,
  • Sudhir U K. Nayak,
  • Vishwapriya Godkhindi,
  • Pallavi Hegde

DOI
https://doi.org/10.4103/ijpd.ijpd_167_21
Journal volume & issue
Vol. 23, no. 2
pp. 159 – 161

Abstract

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Juvenile generalized pustular psoriasis (GPP) is an extremely rare variant of psoriasis, often accompanied by systemic symptoms. It adversely affects the psychosocial aspect of the child as well as their caregivers. Hence, there is a need for rapid control of the disease and induction of remission at the earliest possible time. In this report, we describe a case of a 15-year-old juvenile GPP patient with a history of multiple relapses, who responded dramatically to secukinumab monotherapy. This report is intended to highlight the use of safer biologics such as secukinumab in patients where other conventional drugs are not suitable to use.

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