Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children

Giuseppe Lo Giudice; Fabiana Nicita; Angela Militi; Rossella Bertino; Marco Matarese; Monica Currò; Carmelo  Salpietro Damiano; Carmen Mannucci; Gioacchino Calapai

doi:10.3390/dj8010003

Dentistry Journal (Dec 2019)

Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children

Giuseppe Lo Giudice,
Fabiana Nicita,
Angela Militi,
Rossella Bertino,
Marco Matarese,
Monica Currò,
Carmelo Salpietro Damiano,
Carmen Mannucci,
Gioacchino Calapai

Affiliations

Giuseppe Lo Giudice: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Fabiana Nicita: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Angela Militi: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Rossella Bertino: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Marco Matarese: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Monica Currò: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Carmelo Salpietro Damiano: Department of Adult and Childhood Human Pathology “Gaetano Barresi”, University of Messina, 98100 Messina, Italy
Carmen Mannucci: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy
Gioacchino Calapai: Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98100 Messina, Italy

DOI: https://doi.org/10.3390/dj8010003
Journal volume & issue: Vol. 8, no. 1
p. 3

Abstract

Read online

This study evaluates salivary immunoglobulin A (s-IgA) and interleukin 6 (IL-6) in saliva of children and its correlation to tooth decay severity. Fifty-nine patients were divided into two groups: caries free (A group) and caries active (B group). B group was investigated according to Mount and Monse indices. Mean salivary IgA rate between two groups (A 16.7 ± 4.5 mg/dL vs. B 21.8 ± 12.9 mg/dL) was not significant, while IL-6 rate (A 19.02 ± 5.3 pg/mL vs. B 30.2 ± 11.8 pg/mL) was statistically different. This study revealed that salivary IL-6 levels were significantly higher in children with active caries when compared with the caries-free group, while the s-IgA rate showed no significant differences between the two groups.

Published in Dentistry Journal

ISSN: 2304-6767 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Dentistry
Website: http://www.mdpi.com/journal/dentistry

About the journal

Abstract

Keywords