Two New Sphingolipids from the Leaves of Piper betle L.

Abstract

Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay.

Keywords

• Piper betle L.
• Piperaceae
• sphingolipids
• spectroscopic analysis
• cytotoxic