Limonium duriusculum (de Girard) Kuntze Exhibits Anti-inflammatory Effect Via NF-κB Pathway Modulation

Abstract

HIGHLIGHTS L. duriusculum n-BuOH extract reduces inflammatory responses both in vitro and in vivo. L. duriusculum n-BuOH extract inhibits NF-κB-dependent transcriptional responses. L. duriusculum n-BuOH extract decreases the expression of TNF-α and IL-6 genes.

Keywords

• anti-inflammatory activity
• Limonium duriusculum
• Apigenin derivatives
• n-BuOH extract
• THP-1
• NF-κB
• Immunomodulation