Nox4 expression in osteo-progenitors controls bone development in mice during early life

Affiliations

Jin-Ran Chen: Arkansas Children’s Nutrition Center
Oxana P. Lazarenko: Arkansas Children’s Nutrition Center
Michael L. Blackburn: Arkansas Children’s Nutrition Center
Jennifer F. Chen: Undergraduate Pre-Medical Program, University of Arkansas at Fayetteville
Christopher E. Randolph: Center for Translational Pediatric Research, Arkansas Children’s Research Institute
Jovanny Zabaleta: Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center
Katrin Schroder: Institute of Physiology I, Goethe-University
Kim B. Pedersen: Department of Interdisciplinary Oncology (DIO), Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center
Martin J. J. Ronis: Department of Interdisciplinary Oncology (DIO), Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center

Abstract

Nox4 expression combined with reactive oxygen species signaling are key to osteoblast differentiation, proliferation and maturation in mice.