Clinical significance of obesity measurement indicators and carotid artery plaques in type 2 diabetes

Abstract

Abstract Introduction To investigate the clinical significance of obesity measurement indicators in patients with type 2 diabetes mellitus(T2DM) complicated with carotid plaque. Methods A total of 1009 subjects with T2DM were recruited in the cross-sectional study, and body measurements were collected. According to the results of carotid artery ultrasound, the study subjects were divided into T2DM without carotid plaque group (NCP: n = 617) and with carotid plaque group (WCP: n = 392). Results Compared with the NCP group, the waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), Chinese visceral fat index (CVAI), body roundness index (BRI), body fat index (BAI), body shape index (ABSI), and abdominal volume index (AVI) were significantly increased in the WCP group (P < 0.05). The results of multivariate stepwise logistic regression analysis showed that BAI, CVAI and ABSI had the greatest effect on carotid plaque (P < 0.05). After adjusting for multiple confounding factors, CVAI and ABSI remained independently associated with carotid plaques, and the combination of the three indicators exhibited superior predictive value for carotid plaques. Conclusion CVAI and ABSI are closely related to the occurrence and development of carotid plaque in subjects with T2DM, and the combined application has a good effect on predicting carotid plaque.

Keywords

• Type 2 diabetes mellitus
• Carotid plaque
• CVAI
• ABSI