Nature Communications (Nov 2022)
Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations
- Ketaki Ganti,
- Anish Bagga,
- Silvia Carnaccini,
- Lucas M. Ferreri,
- Ginger Geiger,
- C. Joaquin Caceres,
- Brittany Seibert,
- Yonghai Li,
- Liping Wang,
- Taeyong Kwon,
- Yuhao Li,
- Igor Morozov,
- Wenjun Ma,
- Juergen A. Richt,
- Daniel R. Perez,
- Katia Koelle,
- Anice C. Lowen
Affiliations
- Ketaki Ganti
- Department of Microbiology and Immunology, Emory University School of Medicine
- Anish Bagga
- Emory College of Arts and Sciences
- Silvia Carnaccini
- Department of Population Health, College of Veterinary Medicine, University of Georgia
- Lucas M. Ferreri
- Department of Microbiology and Immunology, Emory University School of Medicine
- Ginger Geiger
- Department of Population Health, College of Veterinary Medicine, University of Georgia
- C. Joaquin Caceres
- Department of Population Health, College of Veterinary Medicine, University of Georgia
- Brittany Seibert
- Department of Population Health, College of Veterinary Medicine, University of Georgia
- Yonghai Li
- Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University
- Liping Wang
- Department of Veterinary Pathobiology, and Department of Molecular Microbiology and Immunology, University of Missouri
- Taeyong Kwon
- Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University
- Yuhao Li
- Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University
- Igor Morozov
- Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University
- Wenjun Ma
- Department of Veterinary Pathobiology, and Department of Molecular Microbiology and Immunology, University of Missouri
- Juergen A. Richt
- Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University
- Daniel R. Perez
- Department of Population Health, College of Veterinary Medicine, University of Georgia
- Katia Koelle
- Department of Biology, Emory University
- Anice C. Lowen
- Department of Microbiology and Immunology, Emory University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-022-34611-z
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 13
Abstract
Virus reassortment drives genetic diversity and evolution and is governed by intra-host dynamics that are less well understood. Here, the authors characterise the within-host dynamics of influenza A virus reassortment in swine, ferrets and guinea pigs, considering their spatial distribution.
