RUDN Journal of Medicine (Dec 2009)

Genetic and morphological factors of nephritic survival rate

  • M I Churnosov,
  • A A Dolzhikov,
  • E V Kalmykova,
  • I K Aristova,
  • V S Vaschilin,
  • V G Nesterov

Journal volume & issue
Vol. 0, no. 4
pp. 370 – 371

Abstract

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The present research is devoted studying of influence of genetic and morphological factors on nephritic survival rate. Interrelation VNTR of polymorphism IL-1Ra with the accelerated falling of function of kidneys is revealed. The factors reducing nephritic survival rate are established: allelic variations -889C IL-1А, -592A IL-10, presence of an arterial hypertensia throughout chronic glomerulonephritis, and also a combination allelic variation -511T IL-1B, presence nefrotic a syndrome and an arterial hypertensia in current chronic glomerulonephritis.

Keywords