ACS Omega
(Aug 2021)
Design and Synthesis of LM146, a Potent Inhibitor of PB1 with an Improved Selectivity Profile over SMARCA2
- Léa Mélin,
- Emily Gesner,
- Sarah Attwell,
- Olesya A. Kharenko,
- Edward H. van der Horst,
- Henrik C. Hansen,
- Alexandre Gagnon
Affiliations
- Léa Mélin
- Département de Chimie, Université du Québec à Montréal, Montréal, Québec, Canada
- Emily Gesner
- Zenith Epigenetics Ltd., Calgary, Alberta, Canada
- Sarah Attwell
- Zenith Epigenetics Ltd., Calgary, Alberta, Canada
- Olesya A. Kharenko
- Zenith Epigenetics Ltd., Calgary, Alberta, Canada
- Edward H. van der Horst
- Zenith Epigenetics Ltd., Calgary, Alberta, Canada
- Henrik C. Hansen
- Zenith Epigenetics Ltd., Calgary, Alberta, Canada
- Alexandre Gagnon
- Département de Chimie, Université du Québec à Montréal, Montréal, Québec, Canada
- DOI
-
https://doi.org/10.1021/acsomega.1c01555
- Journal volume & issue
-
Vol. 6,
no. 33
pp.
21327
– 21338
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