Nature Communications (May 2021)

The genetic architecture of the human thalamus and its overlap with ten common brain disorders

  • Torbjørn Elvsåshagen,
  • Alexey Shadrin,
  • Oleksandr Frei,
  • Dennis van der Meer,
  • Shahram Bahrami,
  • Vinod Jangir Kumar,
  • Olav Smeland,
  • Lars T. Westlye,
  • Ole A. Andreassen,
  • Tobias Kaufmann

DOI
https://doi.org/10.1038/s41467-021-23175-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Differences in thalamic structure have been observed in several psychiatric disorders, but the genetic overlap has not been explored. Here, the authors perform a genome-wide association study on thalamic nuclei volume and find genetic loci in common between thalamic volumes and brain disorders.