Communications Biology (Aug 2021)

Developing ovine mammary terminal duct lobular units have a dynamic mucosal and stromal immune microenvironment

  • Dorottya Nagy,
  • Clare M. C. Gillis,
  • Katie Davies,
  • Abigail L. Fowden,
  • Paul Rees,
  • John W. Wills,
  • Katherine Hughes

DOI
https://doi.org/10.1038/s42003-021-02502-6
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 11

Abstract

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Nagy et al. describe the histomorphogenesis of ovine mammary development in pre- and peri-pubertal sheep as a candidate model for human breast development. They investigate the locale and abundance of several immune cell types at different ages, highlighting this as a valuable model system that can provide new insights into postnatal breast development.