Perforating Gout: Expanding the Differential for Transepidermal Elimination

Abstract

Perforating dermatoses are dermatologic disorders with transepidermal elimination (TE) of dermal substances. While TE is typically associated with collagen and elastin, it can also occur as a secondary event in other processes, and it is important to keep a broad differential. We present a case of perforating tophaceous gout, which underscores the need for a thoughtful approach to perforating disorders. An updated review of recent literature is also presented.

Keywords

• gout
• tophus
• perforating dermatosis
• transepidermal elimination
• pseudoepitheliomatous hyperplasia
• granulomatous dermatitis